A Role for Endotoxin in Obesity

A dysregulated inflammatory response to endotoxin underlies many diseases. Lipopolysaccharide-binding protein (LBP) is a component of the innate immune response that is upregulated during bacteremia or endotoxemia. A recent study by scientists in Spain and published in PLOS-ONE showed high LBP levels in obese patients, suggesting that microbial exposure plays a role in obesity.

Determinants of serum concentrations of lipopolysaccharide-binding protein (LBP) in the adult population: the role of obesity

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